Does Ketamine Last for Depression

Are you going through depression and want to treat it effectively?
It can be hard to deal with depression, especially when standard treatments do not work and everything you have tried hasn’t bought you any relief.
Nevertheless, there is still hope.
Ketamine known for having a quick effect, is helping people with depression who do not respond to other treatments.
So, let’s look into details about ketamine and how long does ketamine last for depression.

An Overview of Ketamine for Depression

Ketamine was originally used as an anesthetic, but now it is known that it can treat depression as well.
It works faster than most antidepressants, and you can usually tell the difference within hours of taking it.

Its unique mechanism involves:

  • Reaching certain brain cells.
  • New brain connections can be formed by releasing brain-derived neurotrophic factor (BDNF).
  • This could bring about positive changes in mood and behavior.

How Long Does Ketamine Last For Depression?

People’s responses to ketamine’s effects can differ.
In the case of depression, ketamine can help quickly, but its effects do not last forever.
Even though it can help for a few days or weeks, to keep the benefits going, it might be necessary to keep consulting a doctor and getting the proper ketamine dosage for depression.

Does Ketamine Therapy Get You High?

When ketamine is used in treatment, you might experience unusual symptoms.
It is possible to feel detached and disconnected from reality or being in dream-like state.
Therefore, when it is used for depression, doctors make sure that it is not intense, overwhelming and doesn’t induce a high.
The focus is on bringing therapeutic effects and treating depression symptoms.

What to Expect After Ketamine Treatment for Depression

After ketamine treatment for depression, you might experience several things, including:

  • Rapid Effects: Some people notice positive changes within hours or a day or two, while others might take a bit longer to feel different.
  • Mood Improvement: You might notice a reduction in depressive symptoms that make you feel sad or hopeless.
  • Energy Boost: You might feel more energetic and motivated.
  • Different Thoughts: Positive changes in thinking patterns or reduced suicidal thoughts may occur.
  • Possible Side Effects: Nausea, dizziness, or feeling “out of it” can happen but usually fade quickly.
  • Continued Treatment: Often, multiple sessions are required for longer-lasting effects. Your healthcare provider will discuss the treatment plan with you and what you can expect.

Side Effects of Ketamine Therapy for Depression

When used to treat depression, ketamine can have the following side effects:

Short-term discomfort.

Common side effects include nausea, vertigo, and headaches, although these tend to go away quickly after treatment.


Feeling cut off from yourself or your surroundings, which could last for a few hours after treatment.

Psychosis risk.

Some people who take ketamine may have delusions or hallucinations.

Physical changes.

Higher blood pressure or heart rate can be dangerous for people with some health problems.

Panic attacks.

Some people may feel anxious or panicked during or after treatment.

Final Thoughts

Do you worry about how long does ketamine last for depression?
It is possible to experience relief almost immediately; however, in order to reap long-term benefits, it is essential to maintain treatment and consult with a healthcare provider.

At Goodness Psychiatry, we offer oral ketamine for treatment-resistant depression.

If your depression, anxiety, or suicidal thoughts do not go away with tradtional treatments, please get in touch with us today.
We can discuss your concerns, help you learn more about this treatment, and help you decide if it is right for you.


1: How much ketamine for depression?

Ketamine dosages will be determined by healthcare professionals based on the patient’s condition and response to treatment.

2: What happens during ketamine therapy?

In most cases, ketamine is administered via an IV infusion in a controlled medical setting.
Patients relax during the session and are monitored by medical staff.

3: How long does ketamine last for depression?

Ketamine’s effects can be immediate, providing relief that lasts for about a week for most people.
However, its duration can be different from person to person.

4: What does ketamine therapy feel like?

During treatment, some people might experience a sense of detachment from reality or a feeling of floating.
However, this differs from person to person, and doctors strive to ensure a positive treatment experience.

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